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AQA GCSE Biology Smart practice A mixed round aimed at your weak spots
Unit 1
Cell biology
Cell division
Chromosomes
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Mitosis and the cell cycle
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Stem cells
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Cell structure
Animal and plant cells
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Cell differentiation
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Cell specialisation
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Culturing microorganisms (biology only)
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Eukaryotes and prokaryotes
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Microscopy
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Transport in cells
Active transport
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Diffusion
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Osmosis
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Unit 2
Organisation
Unit 3
Infection and response
Unit 4
Bioenergetics
Unit 5
Homeostasis and response
Unit 6
Inheritance, variation and evolution
Unit 7
Ecology
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Metabolism

Practise 30 exam-style questions on Metabolism for AQA GCSE Biology. Write your answer as you would in the exam and get it marked in seconds against the mark scheme, point by point, with an AI tutor on hand if you get stuck.

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20 questions, marked as you go

Sample questions with model answers

Here are 4 of the questions in this topic, each with a model answer, an explanation of why it earns the marks and the mark scheme an examiner would use.

Question 1

3 marks

State the role of ATP in metabolism and give one example of a metabolic process that uses ATP.

Model answer

ATP provides energy for cellular processes by hydrolysis to ADP + Pi. Example: active transport, biosynthesis (protein synthesis), muscle contraction.

Explanation

ATP is the immediate energy currency of the cell. Examples of ATP usage include active transport across membranes and anabolic reactions.

Mark scheme
  1. 1 mark

    ATP provides energy for cellular processes / metabolism (ATP ? ADP + Pi releases energy)

  2. 2 marks

    Example e.g., active transport / protein synthesis / muscle contraction

    Award 1 mark for naming a metabolic process and 1 for linking to ATP use.

Question 2

4 marks

Explain why a person continues to breathe deeply for some time after finishing intense exercise (oxygen debt).

Model answer

During intense exercise anaerobic respiration produces lactic acid; extra oxygen post-exercise is needed to oxidise lactic acid to CO2 and H2O and to restore oxygen stores in blood and muscle (myoglobin) and to replenish ATP/creatine phosphate.

Explanation

Oxygen debt: extra post-exercise oxygen metabolises accumulated lactic acid, restores oxygen stores and replenishes high-energy compounds. Each correct component earns marks.

Mark scheme
  1. 1 mark

    Intense exercise leads to anaerobic respiration and lactic acid accumulation

  2. 1 mark

    Extra oxygen after exercise (oxygen debt) is used to oxidise lactic acid (to CO2 and H2O)

  3. 1 mark

    Oxygen is also needed to restore oxygen stores in blood and muscle (myoglobin) and to replenish ATP/creatine phosphate

  4. 1 mark

    Hence breathing remains deep/rapid until recovery processes complete

Question 3

4 marks

Describe how you would calculate the energy transferred by respiration in a food sample using a simple calorimetry experiment with a spirit burner.

Model answer

Burn a known mass of food and use released heat to warm a known mass of water; measure temperature change of water. Energy transferred = mass water × specific heat capacity (4.18 J/g°C) × temperature change divided by mass of food burned (J/g).

Explanation

Method details: control conditions, stir water, insulate, measure mass loss of food, then calculate energy per gram. Award marks for formula and method components.

Mark scheme
  1. 1 mark

    Measure temperature change of a known mass of water heated by combustion

  2. 1 mark

    Calculate energy gained by water = mass water × 4.18 J/g°C × ?T

  3. 1 mark

    Measure mass of food burned to get energy per gram: divide energy by mass burnt (J/g)

  4. 1 mark

    Include controls: insulation, stirring, avoid heat loss (qualitative) to improve accuracy

Question 4

5 marks

Compare the use of carbohydrates, fats and proteins as respiratory substrates during prolonged exercise when glycogen stores are low.

Model answer

Initially carbohydrates (glucose/glycogen) are primary substrate. During prolonged exercise when glycogen is low, fats (fatty acids) become major substrate via beta-oxidation producing acetyl CoA. Proteins can be used by deamination of amino acids but are a minor source and used when other stores low.

Explanation

Expect ordering and reasons: carbohydrate preferred for rapid ATP, fats for long-term energy (more ATP per g), proteins only catabolised when needed; mention oxygen requirement for fatty acid oxidation.

Mark scheme
  1. 2 marks

    Carbohydrates are used first (glucose/glycogen) for rapid ATP; when glycogen low fats become main substrate (beta-oxidation ? acetyl CoA)

  2. 1 mark

    Fats provide more ATP per gram and are used for prolonged energy supply

  3. 1 mark

    Proteins are used as a minor substrate via deamination when other stores are depleted

  4. 1 mark

    Fat oxidation requires more oxygen than carbohydrate (so oxygen availability influences substrate choice)

Ready to try the rest? Every answer you write is marked against the mark scheme, so you can see exactly where the marks are.

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