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AQA GCSE Biology Smart practice A mixed round aimed at your weak spots
Unit 1
Cell biology
Cell division
Chromosomes
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Mitosis and the cell cycle
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Stem cells
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Cell structure
Animal and plant cells
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Cell differentiation
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Cell specialisation
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Culturing microorganisms (biology only)
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Eukaryotes and prokaryotes
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Microscopy
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Transport in cells
Active transport
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Diffusion
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Osmosis
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Unit 2
Organisation
Unit 3
Infection and response
Unit 4
Bioenergetics
Unit 5
Homeostasis and response
Unit 6
Inheritance, variation and evolution
Unit 7
Ecology
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bacterial diseases

Practise 30 exam-style questions on bacterial diseases for AQA GCSE Biology. Write your answer as you would in the exam and get it marked in seconds against the mark scheme, point by point, with an AI tutor on hand if you get stuck.

  • 30 questions
  • 2–5 marks each
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20 questions, marked as you go

Sample questions with model answers

Here are 4 of the questions in this topic, each with a model answer, an explanation of why it earns the marks and the mark scheme an examiner would use.

Question 1

3 marks

Describe briefly how Salmonella causes symptoms in the gut.

Model answer

Bacteria invade gut lining and produce toxins that damage cells, causing inflammation; this leads to vomiting and diarrhoea and abdominal pain.

Explanation

Salmonella multiplies and its toxins damage gut cells, causing inflammation and the typical gastrointestinal symptoms.

Mark scheme
  1. 1 mark

    bacteria / Salmonella infect or invade the gut lining

  2. 1 mark

    they produce toxins / damage cells

  3. 1 mark

    resulting inflammation / irritation causes vomiting/diarrhoea/abdominal pain

Question 2

3 marks

Name one public health reason for making sexually transmitted infections (including gonorrhoea) notifiable in many countries.

Model answer

To enable surveillance and monitoring of incidence and outbreaks and to direct public health resources and interventions such as contact tracing.

Explanation

Notification permits timely public health responses, surveillance and resource targeting to control infectious disease spread.

Mark scheme
  1. 1 mark

    to allow surveillance / monitoring of cases and outbreaks

  2. 1 mark

    to enable public health action (contact tracing / targeted interventions)

  3. 1 mark

    to help control spread and allocate resources

Question 3

4 marks

List two aseptic techniques that should be used when culturing bacteria on agar plates.

Model answer

Flaming loops, sterilising equipment, working near a Bunsen flame or in a clean hood, keeping lids closed, disinfecting bench, washing hands.

Explanation

Aseptic technique prevents contamination of cultures and reduces risk of accidental spread: sterilising equipment, limiting exposure and disinfecting surfaces are key steps.

Mark scheme
  1. 1 mark

    sterilise loop/needle before and after use (e.g. flame)

  2. 1 mark

    minimise plate exposure / keep lids closed / open briefly

  3. 1 mark

    work near a flame / in a sterile cabinet or disinfect bench

  4. 1 mark

    dispose of materials safely and sterilise equipment / wash hands

Question 4

5 marks

Explain how antibiotic resistance arises and why it is a concern for treating bacterial STDs such as gonorrhoea.

Model answer

Random mutations can give bacteria resistance; antibiotics kill sensitive bacteria but resistant ones survive and reproduce, spreading resistance genes. This makes previously effective antibiotics (e.g. penicillin) fail, so gonorrhoea becomes harder to treat and may spread.

Explanation

Resistance emerges by mutation and selection; surviving resistant strains propagate. This reduces treatment options for gonorrhoea and risks more widespread untreatable infections.

Mark scheme
  1. 1 mark

    random mutation or gene transfer can produce resistance in bacteria

  2. 1 mark

    antibiotics kill sensitive bacteria; resistant bacteria survive (selection)

  3. 1 mark

    resistant bacteria reproduce / spread resistance (genes)

  4. 1 mark

    concern: antibiotics that were effective (e.g. penicillin) no longer work

  5. 1 mark

    so infections like gonorrhoea become harder to treat and may spread more

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