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AQA GCSE Biology Smart practice A mixed round aimed at your weak spots
Unit 1
Cell biology
Cell division
Chromosomes
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Mitosis and the cell cycle
0%
Stem cells
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Cell structure
Animal and plant cells
0%
Cell differentiation
0%
Cell specialisation
0%
Culturing microorganisms (biology only)
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Eukaryotes and prokaryotes
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Microscopy
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Transport in cells
Active transport
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Diffusion
0%
Osmosis
0%
Unit 2
Organisation
Unit 3
Infection and response
Unit 4
Bioenergetics
Unit 5
Homeostasis and response
Unit 6
Inheritance, variation and evolution
Unit 7
Ecology
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Cancer

Practise 36 exam-style questions on Cancer for AQA GCSE Biology. Write your answer as you would in the exam and get it marked in seconds against the mark scheme, point by point, with an AI tutor on hand if you get stuck.

  • 36 questions
  • 2–4 marks each
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20 questions, marked as you go

Sample questions with model answers

Here are 4 of the questions in this topic, each with a model answer, an explanation of why it earns the marks and the mark scheme an examiner would use.

Question 1

3 marks

Describe how smoking can increase the risk of lung cancer.

Model answer

Chemicals in tobacco smoke are carcinogens that damage DNA in lung cells. Accumulated DNA damage can cause mutations in genes that control cell division, leading to uncontrolled cell growth (cancer).

Explanation

Carcinogens cause mutations in oncogenes or tumour suppressor genes; when control of cell cycle fails, cells proliferate into tumours in the lungs.

Mark scheme
  1. 1 mark

    tobacco smoke contains carcinogens / chemicals that damage DNA

  2. 1 mark

    DNA damage leads to mutations in genes controlling cell division

  3. 1 mark

    mutations can result in uncontrolled growth / cancer in lung cells

Question 2

3 marks

Explain briefly why secondary tumours are often more serious than the original primary tumour.

Model answer

Secondary tumours (metastases) indicate cancer cells have spread to other organs; multiple tumour sites are harder to treat and can impair functions of vital organs, making prognosis worse.

Explanation

Metastatic disease reflects aggressive cancer biology and often reduces survival because vital organs may be affected and curative local treatment is usually not possible.

Mark scheme
  1. 1 mark

    secondary tumours show cancer has spread to other organs

  2. 1 mark

    multiple sites are harder to treat (surgery/radiation) and drug delivery is more complex

  3. 1 mark

    metastases can impair vital organ function, worsening prognosis

Question 3

3 marks

Why might a doctor recommend genetic counselling for a family with a strong history of a particular cancer?

Model answer

Genetic counselling assesses inherited risk, discusses testing for mutations, explains implications for screening and preventive options, and helps with informed decisions about testing and management.

Explanation

Counselling helps families understand the meaning, options and consequences of genetic test results and cancer risk management strategies.

Mark scheme
  1. 1 mark

    to assess inherited risk / family history of cancer

  2. 1 mark

    to offer tests for mutations and explain implications

  3. 1 mark

    to discuss screening / prevention / informed decision making

Question 4

4 marks

A friend reads that 'eating sugar causes cancer'. Explain how you would evaluate this claim scientifically.

Model answer

Check the evidence: look for peer-reviewed studies, see if studies show correlation or causation; check sample size, controls, and whether confounding factors (obesity, poor diet) were accounted for; rely on systematic reviews and consensus.

Explanation

Scientific claims require critical appraisal: well-designed studies, reproducibility and ruling out confounders are needed before concluding a causal link.

Mark scheme
  1. 1 mark

    look for peer-reviewed scientific studies / reliable sources

  2. 1 mark

    distinguish correlation from causation; check if study shows association only

  3. 1 mark

    check sample size / controls / confounding factors (e.g. obesity)

  4. 1 mark

    give more weight to systematic reviews / meta-analyses / scientific consensus

Ready to try the rest? Every answer you write is marked against the mark scheme, so you can see exactly where the marks are.

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